How to make out the differences between Benign tumour and Malignant tumour

Differences between Benign tumour and Malignant tumour:

  • Benign tumour are;

– Slow growing

– Few mitoses

– Usually resemble tissue of origin

– Nuclear morphology is usually normal

– Usually have a well circumscribed or encapsulated

– Necrosis is rare

– Ulceration is rare

– Never invade

– Never metastasise

  • Malignant tumour are;

– Variable and may be rapid

– Variable but may be many mitoses

– Variable, but may only poorly resemble tissue of origin

– Nuclear morphology may be variable and can be very abnormal with hyperchromasia, pleomorphism and nucleolomegaly

– Often poorly defined or irregular

– Necrosis is common

– Ulceration is common

– May invade surrounding tissues

– May metastasise

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